In the journal Cancer Cell, the team - including scientists from the University of British Columbia (UBC) in Vancouver, Canada - describes how the subsidiary entre halted the layer of various tumors in mice.
While the fact that the joined sugar molecule (a type of chondroitin sulfate) is found in both the placenta and most cancers is not surprising - to the fore both have cells that ensue fast - the evidence for this has without help surfaced recently, as senior author Mads Daugaard, an belt professor of urologic science at UBC, explains:
"Scientists have spent decades maddening to locate biochemical similarities in the middle of placenta tissue and cancer, but we just didn't have the technology to locate it."
Once the team discovered that the malaria parasite uses a protein it produces called VAR2CSA to embed itself in the placenta, they unexpectedly saying the potential to use the process as a enhancement to drive cancer drugs to tumors, he adds.
Malaria protein drug targeted and killed cancer cells, shrank tumors
The researchers - familiar of the irony that one deadly illness offers the means to cure different - tested their idea in two ways: first in cell lines and subsequently in mice, using a drug that combines the malaria protein taking into account an anticancer toxin.
In cell lines, they found that the assimilation drug specifically targeted and killed on peak of 95% of cancer cell lines.
And in mice implanted subsequent to three types of human tumors - the drug along with showed changing degrees of skill. In mice as soon as non-Hodgkin's lymphoma, the treated tumors shrank to a quarter of the size of untreated tumors.
With prostate cancer, the drug certainly eliminated tumors in two of six treated mice within a month of administering the first dose, and considering metastatic breast cancer, five of six treated mice were cured of the sickness.
The researchers say the mice showed no adverse side effects from the treatment and their organs were unharmed by it.
Co-senior author Poul Sorensen, a UBC professor of pathology and laboratory medicine, concludes:
"This is an fantastic finding that paves the pretentiousness for targeting sugar molecules in pediatric and adulthood human cancer, and our groups are energetically pursuing this possibility together."
Two companies, one in Vancouver and the adjunct in Copenhagen, Denmark, where some of the researchers are based, are already developing the drug and preparing it for human trials, which they believe will accept 3-4 years.
Meanwhile, Medical News Today recently literary how nanodiamonds could sponsorship detect cancer to the fore. A investigation published in the journal Nature Communications describes how a nanoscale, synthetic report of diamonds "open happening" prematurely-stage cancers in magnetic resonance imaging (MRI) scans.
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