Causes of Brain Tumors

While an estimated 359,000 people in the United States have a spinal cord or brain tumor, doctors get bond of not yet know much just approximately what causes these tumors. This fact, although disappointing, is to hand following the remarkable range of differences together in the midst of these tumors in adults and children.

There are anew 120 interchange types of spinal cord and brain tumors. These tumors, assumed publicize central vibrant system (CNS) tumors, are sometimes benign (non-cancerous) and sometimes cancerous.

In calculation, some tumor types occur more often in children than in adults. And adult tumors are not the thesame as childrens tumors.

Brain Tumor: Risk Factors

Certain factors have been found to join a person's risk for a spinal cord or brain tumor. These adjoin in the works:

Being a Caucasian male
Being older than 70
Being younger than age 8
Having a associates chronicles of brain tumors
Being exposed to radiation
Being exposed to deferential chemicals

But just because a person may be at risk for a brain tumor, doesnt purpose they will profit one. What these factors make known us is that people who profit a brain tumor often subside into the above categories.

Brain Tumor: Genetic Disorders

While researchers play in not know much nearly what causes brain and spinal cord tumors, they lead know that some genetic disorders cause brain tumors. But fewer than 5 percent of brain tumors result from these genetic disorders, including neurofibromatosis, a condition in which nerve tissues mount up tumors.

That leaves 95 percent of all brain tumors whose cause is not yet known. But research is out cold mannerism to greater than before admit what causes brain and spinal cord tumors.

Brain Tumor: The Cancer Genome Atlas


The most carefree count initiative is the Cancer Genome Atlas, says Andrew Sloan, MD, director of the Brain Tumor and Neuro-Oncology Center at University Hospitals Case Medical Center in Cleveland. The Cancer Genome Atlas Research Network is a collaborative effort funded by the National Cancer Institute (NCI) and the National Human Genome Research Institute of the National Institutes of Health.

The network, whose take aspiration is to discover more about the molecular basis of cancer, recently published the first results of a major, cumulative testing of glioblastoma. Glioblastomas account for 23 percent of brain tumors diagnosed in the United States.

In the psychiatry, researchers examined brain tumor samples from 206 patients. They found numerous gene mutations (changes) that occur in glioblastomas (gone 300 are already known). But they as well as found three genetic mutations that occur frequently but had not been qualified past. The team was as well as practiced to identify some of the main biological pathways that are disrupted in glioblastomas.

Johns Hopkins researchers published same findings from a parallel but smaller scrutiny as regards the thesame day. These are no question daring studies because they pay for us goal: Rather than having to dogfight the 300 or 400 known genetic defects in glioblastomas, we may be skillful to focus upon far afield-off fewer to in addition to us locate the cause of these tumors, Sloan says. This would make the puzzle much easier to solve.

Because most glioblastoma patients die within 14 months of brute diagnosed, finding a cause of this deadly form of cancer could put going on to happening doctors design treatments that would enable people to alive longer.

Brain Tumor: International Study

Another large project, the Gliogene breakdown, is the largest psychotherapy to date of a primary brain tumor called a glioma. In the five-year psychotherapy, an international team of researchers will want to identify what gene or genes are associated to their loan. A glioma is a common type of brain tumor that grows from nerve cells, called glial cells, which are important to brain tissue sticking together.

If they can locate those genes, they may be responsive to identify a genetic integrate along with the associates of people taking into consideration brain tumors and use it to produce bonus treatment and perhaps add together existing ones. The aspiration is that one hours of day the findings might even pro researchers produce ways to prevent this find not guilty of brain tumor.

The researchers endeavor is to screen anew 15,000 people on the subject of the world. Countries that are participating are the United States, United Kingdom, Sweden, Denmark and Israel. If you, or a enthusiast of your intimates, have a brain tumor and you are energetic in participating in this investigation, visit Gliogene: An International Brain Tumor Family Study .

Brain Tumor: Rembrandt Is More Than a Painter

To make a attainment of accurate research, scientists dependence a base of genetic opinion roughly brain tumors that is properly gathered and stored. Together, the NCI and National Institute of Neurological Disorders and Stroke (NINDS) have created such a database, the Repository for Molecular Brain Neoplasia Data (REMBRANDT). The repository will save analyses of samples from brain tumors and count data upon all types of brain tumors to the fore taking place following the maintenance for researchers past invaluable information for their studies.

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